American Research Journal of Pharmacy          cover
Open Access

American Research Journal of Pharmacy

ISSN (Online): 2380-5706

DOI: 10.46568/arjpm

Case Report Vol. 6, Issue 1 2025 Open Access

A Case Report of Peripheral Cyanosis Associated with a Rare Adverse Reaction of Vaxzevria - AstraZeneca COVID-19 Vaccine

T. Pham Viet1, P. Thai Phuong1, T. Bui-Viet1, A. Nguyen Thi Ngoc1, H. Tran Quoc2, S. Duong Quy2,3,4 

1Ninh Thuan General Hospital, Ninh Thuan province, Viet Nam.

2Lam Dong Medical College, Da Lat, Viet Nam.

3Penn State Medical College, Pennsylvania, USA.

4Pham Ngoc Thach Medical University, Ho Chi Minh city, Viet Nam.

Abstract
In the current pandemic of SARS-CoV-2, the fast development ofvaccines was mandatory due to many deaths and cases across theworld since the beginning of the outbreak. The European Medicines Agency (EMA) has allowed emergency use authorization for treatment with the Vaxzevria (ChAdOx1-S, AstraZeneca) vaccines in the European Union. There are a lot of adverse drug reactions observed during the vaccination campaign, the most common side effects are tenderness, pain and bruising at the injection site, headache, tiredness, muscle pain, general feeling of being unwell, chills, fever, joint pain and nausea (feeling sick), and can also rarely cause anaphylactic shock. The recognition of adverse drug reactions of the vaccine Vaxzevria plays an important role in minimizing vaccine-induced adverse reactions. In this report, we record and analyze a rare case of peripheral cyanosis appearing after being vaccinated, and sharing the way to resolve this problem to contribute to the data of adverse drugs reaction regarding Vaxzevria.