Open Access
American Research Journal of Cardiovascular Diseases
ISSN (Online): 2575-7601
DOI: 10.46568/arjcd
Can Skin Sign and Symptoms be an Indicator of Excessive Antihyperlipidemic Treatment in Heart Failure Patients?
Department of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, United States of America
Abolfazl Dohaei, “Can Skin Sign and Symptoms be an Indicator of Excessive Antihyperlipidemic
Treatment in Heart Failure Patients?”. American Research Journal of Cardiovascular Diseases, 3(1); pp: 1-3.
Abstract
Morbidities following antihyperlipidemic treatmentsuch as muscular and hepatic disorders have
been reported in the literature. According to new guidelines high intensity antihyperlipidemic therapy is a class
I recommendation for patients with clinical atherosclerotic cardiovascular disease or low density lipoprotein
cholesterol ≥ 190 milligram per deciliter, although existing data regarding initiation or continuation of statin
therapy in symptomatic heart failure patients (New York Heart Association Class II-IV) are equivocal. I sought to
evaluate morbidities associated with unproven treatment in heart failure patients because it may decrease the
number of problems in these patients which is very valuable. Based upon the experience of seeing and treating
patients with heart failure, I have observed signs and symptoms of skin dryness and pruritus in these patients
which was related to their antihyperlipidemic treatment. This relationship was supported by the disappearance
of these signs and symptoms after discontinuing their antihyperlipidemic drug and increasing fat in their diet.
Improvement was seen by the next visit within one to two months of the intervention. I also observed that some
of these patients had been treated for their symptoms with treatments for dermatitis and without response
to topical treatment. Evaluation of clinicalsign and symptomsof skin dryness and pruritus related to extreme
antihyperlipidemic treatment is important, because it decreases the number of morbiditiesin heart failure
patients and prevents inappropriate andpotentiallydeleterious therapies.