American Research Journal of Urology

Hereditary leiomyomatosis and renal cell carcinoma is an autosomal dominant condition associated with multiple cutaneous and uterine leiomyomas associated with renal cell carcinoma. This syndrome has been proposed to be a variant of Reed’s syndrome, which is also called as multiple cutaneous and uterine leiomyomatosis. Carcinomas in this syndrome tend to be more aggressive than the normal sporadic renal cell cancers. Urologists tend to miss out these skin lesions which can act as a markers of underlying renal cell cancer. Similarly Dermatologists can ignore the screening of such patients with skin lesions for underlying renal carcinoma. In this article we present a case of hereditary leiomyomatosis and renal cell carcinoma, a variant of Reed’s syndrome.